Article
Interactive transcriptome analysis of malaria patients and infecting Plasmodium falciparum.
Genome research - 1 Sept 2014
Yamagishi Junya, Natori Anna, Tolba Mohammed E M, Mongan Arthur E, Sugimoto Chihiro, Katayama Toshiaki, Kawashima Shuichi, Makalowski Wojciech, Maeda Ryuichiro, Eshita Yuki, Tuda Josef, Suzuki Yutaka
Abstract excerpt
To understand the molecular mechanisms of parasitism in vivo, it is essential to elucidate how the transcriptomes of the human hosts and the infecting parasites affect one another. Here we report the RNA-seq analysis of 116 Indonesian patients infected with the malaria parasite Plasmodium falciparum (Pf). We extracted RNAs from their peripheral blood as a mixture of host and parasite transcripts and mapped the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.