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Malian children infected with Plasmodium ovale and Plasmodium falciparum display very similar gene expression profiles

25 Jan 2023

Abstract excerpt

Plasmodium parasites caused 241 million cases of malaria and over 600,000 deaths in 2020. Both P. falciparum and P. ovale are endemic to Mali and cause clinical malaria, with P. falciparum infections typically being more severe. Here, we sequenced RNA from nine pediatric blood samples collected during infections with either P. falciparum or P. ovale, and characterized the host and parasite gene expression...

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PMID: 36696438
DOI: 10.1371/journal.pntd.0010802

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