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Article

AraC-Type Regulator Rbf Controls the Staphylococcus epidermidis Biofilm Phenotype by Negatively Regulating the icaADBC Repressor SarR.

Journal of bacteriology - 1 Nov 2016

Rowe Sarah E, Campbell Christopher, Lowry Colm, O'Donnell Sinead T, Olson Michael E, Lindgren Jill K, Waters Elaine M, Fey Paul D, O'Gara James P

Abstract excerpt

Regulation of icaADBC-encoded polysaccharide intercellular adhesin (PIA)/poly-N-acetylglucosasmine (PNAG) production in staphylococci plays an important role in biofilm-associated medical-device-related infections. Here, we report that the AraC-type transcriptional regulator Rbf activates icaADBC operon transcription and PIA production in Staphylococcus epidermidis Purified recombinant Rbf did not bind to the ica...

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Identifiers

PMID: 27501984
DOI: 10.1128/JB.00374-16
PMCID: PMC5055596

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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AraC-Type Regulator Rbf Controls the Staphylococcus epidermidis Biofilm Phenotype by Negatively Regulating the icaADBC Repressor SarR.PMID 27501984Read ↗

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