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Article

Combinatorial extracellular matrix microenvironments promote survival and phenotype of human induced pluripotent stem cell-derived endothelial cells in hypoxia.

Acta biomaterialia - 15 Oct 2016

Hou Luqia, Coller John, Natu Vanita, Hastie Trevor J, Huang Ngan F

Abstract excerpt

UNLABELLED: Recent developments in cell therapy using human induced pluripotent stem cell-derived endothelial cells (iPSC-ECs) hold great promise for treating ischemic cardiovascular tissues. However, poor post-transplantation viability largely limits the potential of stem cell therapy. Although the extracellular matrix (ECM) has become increasingly recognized as an important cell survival factor, conventional...

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Identifiers

PMID: 27498178
DOI: 10.1016/j.actbio.2016.08.003
PMCID: PMC5045796

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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