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Laminin-guided highly efficient endothelial commitment from human pluripotent stem cells

2 Nov 2016

Abstract excerpt

Obtaining highly purified differentiated cells via directed differentiation from human pluripotent stem cells (hPSCs) is an essential step for their clinical application. Among the various conditions that should be optimized, the precise role and contribution of the extracellular matrix (ECM) during differentiation are relatively unclear. Here, using a short fragment of laminin 411 (LM411-E8), an ECM...

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PMID: 27804979
DOI: 10.1038/srep35680

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