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Combinatorial Extracellular Matrices for Human Embryonic Stem Cell Differentiation in 3D

9 Jul 2010

Abstract excerpt

Embryonic stem cells (ESCs) are promising cell sources for tissue engineering and regenerative medicine. Scaffolds for ESC-based tissue regeneration should provide not only structural support, but also signals capable of supporting appropriate cell differentiation and tissue development. Extracellular matrix (ECM) is a key component of the stem cell niche in vivo and can influence stem cell fate via mediating...

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PMID: 20614932
DOI: 10.1021/bm100357t

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