Article
Analysis of neural crest-derived clones reveals novel aspects of facial development.
Science advances - 1 Aug 2016
Kaucka Marketa, Ivashkin Evgeny, Gyllborg Daniel, Zikmund Tomas, Tesarova Marketa, Kaiser Jozef, Xie Meng, Petersen Julian, Pachnis Vassilis, Nicolis Silvia K, Yu Tian, Sharpe Paul, Arenas Ernest, Brismar Hjalmar, Blom Hans, Clevers Hans, Suter Ueli, Chagin Andrei S, Fried Kaj, Hellander Andreas, Adameyko Igor
Abstract excerpt
Cranial neural crest cells populate the future facial region and produce ectomesenchyme-derived tissues, such as cartilage, bone, dermis, smooth muscle, adipocytes, and many others. However, the contribution of individual neural crest cells to certain facial locations and the general spatial clonal organization of the ectomesenchyme have not been determined. We investigated how neural crest cells give rise to...
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