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Clonal analysis reveals common lineage relationships between head muscles and second heart field derivatives in the mouse embryo

7 Sept 2010

Abstract excerpt

Head muscle progenitors in pharyngeal mesoderm are present in close proximity to cells of the second heart field and show overlapping patterns of gene expression. However, it is not clear whether a single progenitor cell gives rise to both heart and head muscles. We now show that this is the case, using a retrospective clonal analysis in which an nlaacZ sequence, converted to functional nlacZ after a rare...

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PMID: 20823066
DOI: 10.1242/dev.050674

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