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Article

Neural crest–derived cells with stem cell features can be traced back to multiple lineages in the adult skin

11 Dec 2006

Abstract excerpt

Given their accessibility, multipotent skin-derived cells might be useful for future cell replacement therapies. We describe the isolation of multipotent stem cell-like cells from the adult trunk skin of mice and humans that express the neural crest stem cell markers p75 and Sox10 and display extensive self-renewal capacity in sphere cultures. To determine the origin of these cells, we genetically mapped the fate...

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PMID: 17158956
DOI: 10.1083/jcb.200606062

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