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Article

FGF8 and Shh promote the survival and maintenance of multipotent neural crest progenitors.

Mechanisms of development - 1 Dec 2018

da Costa Meline Coelho, Trentin Andréa Gonçalves, Calloni Giordano Wosgrau

Abstract excerpt

The developmental mechanisms that control the building of the complex head of vertebrates and particularly, facial skeletogenesis, remain poorly known. Progenitor cells derived from the embryonic neural crest (NC) are the major constituents and players of facial tissue development. Deciphering the cellular and molecular machinery that controls NC cell (NCC) differentiation into bone, cartilage, fat and other...

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Identifiers

PMID: 30075227
DOI: 10.1016/j.mod.2018.07.012

Genes

FGF8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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