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Susceptibility to the larvicide pyriproxyfen and genotyping of kdr mutations in two Aedes aegypti populations from Maranhão State, Brazil.

Acta tropica - 1 Feb 2026

Pinheiro Valéria Cristina Soares, Viana Juliete Lima, da Silva Joelma Soares, Gonçalves Márcia Verônica Pereira, Andrade Aylane Tamara Dos Santos, Brito Luiz Paulo, Martins Ademir Jesus

Abstract excerpt

Aedes aegypti is the main vector of arboviruses in the Americas, including dengue, Zika and chikungunya. In Brazil, initial control strategies relied on insecticides, but their continuous use has promoted resistance, mainly through metabolic changes and knockdown resistance (kdr) mutations, which are key molecular markers of pyrethroid resistance. This study evaluated the susceptibility of Ae. aegypti populations...

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PMID: 41397552
DOI: 10.1016/j.actatropica.2025.107946

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