Nociceptin/orphanin FQ receptor gene variation is associated with smoking status in Japanese.

doi:10.2217/pgs.15.184

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Article

Nociceptin/orphanin FQ receptor gene variation is associated with smoking status in Japanese.

Pharmacogenomics - 1 Aug 2016

Kasai Shinya, Nishizawa Daisuke, Hasegawa Junko, Sato Naomi, Tanioka Fumihiko, Sugimura Haruhiko, Ikeda Kazutaka

Abstract excerpt

AIM: The endogenous opioid system has been reportedly implicated in tobacco/nicotine dependence. MATERIALS & METHODS: We examined the genetic effects of eight SNPs in opioid receptor-related genes on smoking status and smoking-related traits in Japanese. RESULTS: The genotypic and allelic variations of the rs2229205 SNP in the OPRL1 gene were significantly associated with smoking status, but no significant...

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PMID: 27491383
DOI: 10.2217/pgs.15.184

Genes

OPRL1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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