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Article

Impact of donor-recipient phylogenetic distance on bacterial genome transplantation.

Nucleic acids research - 30 Sept 2016

Labroussaa Fabien, Lebaudy Anne, Baby Vincent, Gourgues Géraldine, Matteau Dominick, Vashee Sanjay, Sirand-Pugnet Pascal, Rodrigue Sébastien, Lartigue Carole

Abstract excerpt

Genome transplantation (GT) allows the installation of purified chromosomes into recipient cells, causing the resulting organisms to adopt the genotype and the phenotype conferred by the donor cells. This key process remains a bottleneck in synthetic biology, especially for genome engineering strategies of intractable and economically important microbial species. So far, this process has only been reported using...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 27488189
DOI: 10.1093/nar/gkw688
PMCID: PMC5041484

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Source receipt: pubmed, retrieved 7 Sept 2026.

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