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Key experimental evidence of chromosomal DNA transfer among selected tuberculosis-causing mycobacteria

15 Aug 2016

Abstract excerpt

Horizontal gene transfer (HGT) is a major driving force of bacterial diversification and evolution. For tuberculosis-causing mycobacteria, the impact of HGT in the emergence and distribution of dominant lineages remains a matter of debate. Here, by using fluorescence-assisted mating assays and whole genome sequencing, we present unique experimental evidence of chromosomal DNA transfer between tubercle bacilli of...

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PMID: 27528665
DOI: 10.1073/pnas.1604921113

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