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Genetic Analysis of Mismatch Repair Genes Alterations in Extramammary Paget Disease

9 Aug 2016

Abstract excerpt

Extramammary Paget disease (EMPD) is a rare cutaneous malignant neoplasm. The familial occurrence of EMPD and the high risk of concomitant secondary tumors in EMPD patients have gained much attention. These findings highlight the importance of genetic alterations in the tumorigenesis of this skin cancer. Genetic tests and functional analysis of mismatch repair (MMR) genes were performed in EMPD. The results...

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PMID: 27487738
DOI: 10.1097/pas.0000000000000709

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