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Article

Family with MSH2 mutation presenting with keratoacanthoma and precancerous skin lesions.

The Journal of dermatology - 1 Nov 2015

Hatta Naohito, Takata Akiko, Ishizawa Shin, Niida Yo

Abstract excerpt

Muir-Torre syndrome (MTS) is a familial cancer syndrome characterized by a predisposition to keratoacanthoma (KA) and sebaceous tumors. Although MTS and hereditary non-polyposis colorectal cancer (HNPCC) share the same genetic alterations in mismatch repair (MMR) genes, the other skin lesions in MTS or HNPCC have been only rarely reported. We report a family with an MSH2 mutation c.1126_1127delTT...

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Identifiers

PMID: 26077460
DOI: 10.1111/1346-8138.12949

Genes

MSH2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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