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Article

Spike gene deletion quasispecies in serum of patient with acute MERS-CoV infection.

Journal of medical virology - 1 Mar 2017

Lu Xiaoyan, Rowe Lori A, Frace Michael, Stevens James, Abedi Glen R, Elnile Osman, Banassir Taleb, Al-Masri Malak, Watson John T, Assiri Abdullah, Erdman Dean D

Abstract excerpt

The spike glycoprotein of the Middle East respiratory coronavirus (MERS-CoV) facilitates receptor binding and cell entry. During investigation of a multi-facility outbreak of MERS-CoV in Taif, Saudi Arabia, we identified a mixed population of wild-type and variant sequences with a large 530 nucleotide deletion in the spike gene from the serum of one patient. The out of frame deletion predicted loss of most of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27486688
DOI: 10.1002/jmv.24652
PMCID: PMC7166981

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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