Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human ULK1 Variation and Susceptibility to Mycobacterium tuberculosis Infection.

The Journal of infectious diseases - 15 Oct 2016

Horne David J, Graustein Andrew D, Shah Javeed A, Peterson Glenna, Savlov Meg, Steele Sergio, Narita Masahiro, Hawn Thomas R

Abstract excerpt

BACKGROUND: Unlike tuberculosis, few studies have evaluated a host genetic basis for variability in susceptibility to latent Mycobacterium tuberculosis infection (LTBI). We performed a candidate gene association study of autophagy-related genes and LTBI. METHODS: We enrolled close contacts of individuals with pulmonary tuberculosis, assessed LTBI status, and determined clinical and sociodemographic risk factors...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Signal Transducing
Share to Apoptosis Regulatory Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intracellular Signaling Peptides and Proteins

Share to Latent Tuberculosis

Share to Microtubule-Associated Proteins

Share to Mycobacterium tuberculosis

Share to Tuberculosis, Pulmonary

Share to U937 Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 27485354
DOI: 10.1093/infdis/jiw347
PMCID: PMC5034956

Genes

ULK1
GABARAP
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human ULK1 Variation and Susceptibility to Mycobacterium tuberculosis Infection.PMID 27485354Read ↗

Association of polymorphisms and abnormal methylation of several autophagy genes with pulmonary tuberculosis susceptibility, clinical manifestations in a Chinese population.Semantic proximity Read ↗

Human genetic background in susceptibility to tuberculosis.Semantic proximity Read ↗

Association between ULK1 gene polymorphisms and susceptibility to multisystem tuberculosisSemantic proximity Read ↗

LncRNA MIAT regulates autophagy and apoptosis of macrophage infected by Mycobacterium tuberculosis through the miR-665/ULK1 signaling axisSemantic proximity Read ↗

Phagosomal RNA sensing through TLR8 controls susceptibility to tuberculosisSemantic proximity Read ↗

The role of autophagy in host defence against Mycobacterium tuberculosis infection.Semantic proximity Read ↗

Mycobacterium tuberculosis, macrophages, and the innate immune response: does common variation matter?Semantic proximity Read ↗

Association between IRGM polymorphisms and tuberculosis risk: A meta-analysis.Semantic proximity Read ↗

Tuberculosis and impaired IL-23–dependent IFN-γ immunity in humans homozygous for a common TYK2 missense variantSemantic proximity Read ↗

The monogenic basis of human tuberculosis.Semantic proximity Read ↗

Leprosy susceptibility: genetic variations regulate innate and adaptive immunity, and disease outcome.Semantic proximity Read ↗

A Functional Toll-Interacting Protein Variant Is Associated with Bacillus Calmette-Guérin-Specific Immune Responses and Tuberculosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.