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Article

OPRM1 genotype interacts with serotonin system dysfunction to predict alcohol-heightened aggression in primates.

Addiction biology - 1 Nov 2017

Driscoll Carlos A, Lindell Stephen G, Schwandt Melanie L, Suomi Stephen J, Higley J Dee, Heilig Markus, Barr Christina S

Abstract excerpt

Although the notion that alcohol promotes violence is widespread, not all individuals are aggressive while intoxicated. Genetic variation could be a contributing factor to individual differences in alcohol-heightened aggression. The present study examines the effects of OPRM1C77G genotype on responses to threat in rhesus macaques under normal conditions and following alcohol administration. Prior studies have...

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Source

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Identifiers

PMID: 27484010
DOI: 10.1111/adb.12428
PMCID: PMC5290299

Genes

OPRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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