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Article

MTHFR and ACE Polymorphisms Do Not Increase Susceptibility to Migraine Neither Alone Nor in Combination.

Headache - 1 Sept 2016

Essmeister Rafaela, Kress Hans-Georg, Zierz Stephan, Griffith Lyn, Lea Rod, Wieser Thomas

Abstract excerpt

OBJECTIVE: The aim of this study was to confirm previous reports in order to substantiate the hypothesis that functional variants of two genes, namely methylenetetrahydrofolate reductase and angiotensin I converting enzyme, both involved in an important pathway of migraine, increase migraine susceptibility when present in combination. BACKGROUND: Migraine is a complex genetic disease. The migraine attack is...

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Source

Identifiers

PMID: 27483173
DOI: 10.1111/head.12893

Genes

ACE
MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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