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Article

Genetic variants of angiotensin converting enzyme and methylenetetrahydrofolate reductase may act in combination to increase migraine susceptibility.

Brain research. Molecular brain research - 20 May 2005

Lea Rod A, Ovcaric Micky, Sundholm James, Solyom Leah, Macmillan John, Griffiths Lyn R

Abstract excerpt

Migraine, with and without aura (MA and MO), is a prevalent and complex neurovascular disorder that is likely to be influenced by multiple genes some of which may be capable of causing vascular changes leading to disease onset. This study was conducted to determine whether the ACE I/D gene variant is involved in migraine risk and whether this variant might act in combination with the previously implicated MTHFR...

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Source

Identifiers

PMID: 15893594
DOI: 10.1016/j.molbrainres.2005.01.006

Genes

ACE
MTHFR

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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