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Article

A Comprehensive Review on the Role of Genetic Factors in the Pathogenesis of Migraine.

Journal of molecular neuroscience : MN - 1 Oct 2021

Ebahimzadeh Kaveh, Gholipour Mahdi, Samadian Mohammad, Taheri Mohammad, Ghafouri-Fard Soudeh

Abstract excerpt

Migraine is a common neurovascular condition. This disorder has a complex genetic background. Several single-nucleotide polymorphisms (SNPs) or mutations within genes regulating glutamatergic neurotransmission, cortical excitability, ion channels, and solute carriers have been associated with polygenic and monogenic forms of migraine. SNPs within ACE, DBH, TRPM8, COMT, GABRQ, CALCA, TRPV1, and other genes have...

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PMID: 33447900
DOI: 10.1007/s12031-020-01788-1

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