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Article

Broadly Neutralizing Activity of Zika Virus-Immune Sera Identifies a Single Viral Serotype

30 Jul 2016

Abstract excerpt

Recent epidemics of Zika virus (ZIKV) have been associated with congenital malformation during pregnancy and Guillain-Barré syndrome. There are two ZIKV lineages (African and Asian) that share >95% amino acid identity. Little is known regarding the ability of neutralizing antibodies elicited against one lineage to protect against the other. We investigated the breadth of the neutralizing antibody response...

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PMID: 27481466
DOI: 10.1016/j.celrep.2016.07.049

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