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Article

Associations of tumor somatic mutations with cancer-associated venous thromboembolism.

Journal of thrombosis and haemostasis : JTH - 1 May 2026

Cornish Naomi, Ward Rebecca, Warkentin Matthew T, Thirlwell Chrissie, Mumford Andrew D, Westbury Sarah K, Haycock Philip C

Abstract excerpt

BACKGROUND: Venous thromboembolism (VTE) is a common complication of cancer. Complex interactions between tumor biology and the hemostatic system contribute to development of cancer-associated thrombosis. OBJECTIVES: This study examined associations of somatic mutations with VTE in a large multicancer cohort. METHODS: We analyzed paired tumor and germline whole genome sequence data and electronic health records...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41692092
DOI: 10.1016/j.jtha.2026.01.019

Genes

PCDH15
CDKN2A
KRAS
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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