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Article

[Molecular biology of castration-resistant prostate cancer].

Bulletin du cancer - 1 Jun 2015

Doucet Ludovic, Terrisse Safae, Gauthier Hélène, Pouessel Damien, Le Maignan Christine, Teixeira Luis, Culine Stéphane

Abstract excerpt

Castration-resistant prostate cancer was subjected to a paradigm switch from hormone resistance to androgen deprivation therapy resistance during the last decade. Indeed, new therapeutics targeting the androgen receptor showed clinical efficacy in patients with progressive disease under castration. Thus, it is a proof that the AR remains a dominant driver of oncogenesis in earlier-called hormone resistant...

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Source

Identifiers

PMID: 26028493
DOI: 10.1016/j.bulcan.2015.04.014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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