Article
Genomic/Epigenomic Alterations in Ovarian Carcinoma: Translational Insight into Clinical Practice
1 Jan 2016
Abstract excerpt
Ovarian carcinoma is the most lethal gynecological malignancy worldwide. Recent advance in genomic/epigenomic researches will impact on our prevention, detection and intervention on ovarian carcinoma. Detection of germline mutations in BRCA1/BRCA2, mismatch repair genes, and other genes in the homologous recombination/DNA repair pathway propelled the genetic surveillance of most hereditary ovarian carcinomas....
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