Article
Inhibition of autophagy sensitizes MDR-phenotype ovarian cancer SKVCR cells to chemotherapy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Aug 2016
Liang Bing, Liu Xiaodong, Liu Yang, Kong Dejuan, Liu Xiaomei, Zhong Rui, Ma Shumei
Abstract excerpt
UNLABELLED: AUTOPHAGY: is an intracellular lysosomal degradation pathway where its primary function is to allow cells to survive under stressful conditions. Autophagy is, however, a double-edge sword that can either promote cell survival or cell death. CHEMORESISTANCE: is a major challenge in the clinical treatment of ovarian cancer, of which the underlying mechanisms remain unknown. OBJECTIVE: The aim of the...
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