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Article

The different regulatory effects of p53 status on multidrug resistance are determined by autophagy in ovarian cancer cells.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Jun 2012

Kong Dejuan, Ma Shumei, Liang Bing, Yi Heqing, Zhao Yinlong, Xin Rui, Cui Li, Jia Lili, Liu Xin, Liu Xiaodong

Abstract excerpt

PURPOSE: Multidrug resistance (MDR) has become an obstacle for chemotherapy of cancer. p53 is reported to participate in the regulation of MDR, but the association between p53 status and MDR are complicated and conditional. It has been verified that apoptosis is not the only mechanism for MDR regulation by p53, the roles of autophagy in MDR is less studied. PATIENTS AND METHODS: Human ovarian carcinoma cell lines...

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Identifiers

PMID: 22564245
DOI: 10.1016/j.biopha.2011.12.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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