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Autophagy and multidrug resistance in cancer

24 Jun 2017

Abstract excerpt

Multidrug resistance (MDR) occurs frequently after long-term chemotherapy, resulting in refractory cancer and tumor recurrence. Therefore, combatting MDR is an important issue. Autophagy, a self-degradative system, universally arises during the treatment of sensitive and MDR cancer. Autophagy can be a double-edged sword for MDR tumors: it participates in the development of MDR and protects cancer cells from...

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PMID: 28646911
DOI: 10.1186/s40880-017-0219-2

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