Article
ATRX in Diffuse Gliomas With its Mosaic/Heterogeneous Expression in a Subset.
Brain pathology (Zurich, Switzerland) - 1 Mar 2017
Purkait Suvendu, Miller Christopher A, Kumar Anupam, Sharma Vikas, Pathak Pankaj, Jha Prerana, Sharma Mehar Chand, Suri Vaishali, Suri Ashish, Sharma B S, Fulton Robert S, Kale Shashank Sharad, Dahiya Sonika, Sarkar Chitra
Abstract excerpt
This study aims (1) to evaluate ATRX expression in different grades and subtypes of gliomas and correlate with other hallmark genetic alterations, (2) to identify and characterize mosaic/heterogeneous staining in gliomas in terms of mutation status. One hundred seventy six cases of glioma were assessed for ATRX immunohistochemistry and subdivided into positive, negative and mosaic/heterogeneous staining patterns....
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