Article
Genomewide association studies of stroke.
The New England journal of medicine - 23 Apr 2009
Ikram M Arfan, Seshadri Sudha, Bis Joshua C, Fornage Myriam, DeStefano Anita L, Aulchenko Yurii S, Debette Stephanie, Lumley Thomas, Folsom Aaron R, van den Herik Evita G, Bos Michiel J, Beiser Alexa, Cushman Mary, Launer Lenore J, Shahar Eyal, Struchalin Maksim, Du Yangchun, Glazer Nicole L, Rosamond Wayne D, Rivadeneira Fernando, Kelly-Hayes Margaret, Lopez Oscar L, Coresh Josef, Hofman Albert, DeCarli Charles, Heckbert Susan R, Koudstaal Peter J, Yang Qiong, Smith Nicholas L, Kase Carlos S, Rice Kenneth, Haritunians Talin, Roks Gerwin, de Kort Paul L M, Taylor Kent D, de Lau Lonneke M, Oostra Ben A, Uitterlinden Andre G, Rotter Jerome I, Boerwinkle Eric, Psaty Bruce M, Mosley Thomas H, van Duijn Cornelia M, Breteler Monique M B, Longstreth W T, Wolf Philip A
Abstract excerpt
BACKGROUND: The genes underlying the risk of stroke in the general population remain undetermined. METHODS: We carried out an analysis of genomewide association data generated from four large cohorts composing the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium, including 19,602 white persons (mean [+/-SD] age, 63+/-8 years) in whom 1544 incident strokes (1164 ischemic strokes) developed...
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