Article

Clinical exome sequencing for stroke evaluation uncovers a high frequency of Mendelian disorders: a retrospective analysis

2022-06-14

Abstract excerpt

<h4>Background</h4> Stroke causes significant disability and is a common cause of death worldwide. Previous studies have estimated that 1-5% of stroke is attributable to monogenic etiologies. We set out to assess the utility of clinical exome sequencing (ES) in the evaluation of stroke. <h4>Methods</h4> We retrospectively analyzed 124 individuals who received ES at the Baylor Genetics reference lab between 2012 an...

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Literature Corpus work: 0ba1e65a-dd01-50c4-8200-3778797b3fe6
DOI: 10.1101/2022.06.10.22276114

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