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Article

An investigation of the association of genetic susceptibility risk with somatic mutation burden in breast cancer.

British journal of cancer - 6 Sept 2016

Zhu Bin, Mukherjee Anwesha, Machiela Mitchell J, Song Lei, Hua Xing, Shi Jianxin, Garcia-Closas Montserrat, Chanock Stephen J, Chatterjee Nilanjan

Abstract excerpt

BACKGROUND: Genome-wide association studies have reported nearly 100 common germline susceptibility loci associated with the risk for breast cancer. Tumour sequencing studies have characterised somatic mutation profiles in breast cancer patients. The relationship between breast cancer susceptibility loci and somatic mutation patterns in breast cancer remains largely unexplored. METHODS: We used single-nucleotide...

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Identifiers

PMID: 27467053
DOI: 10.1038/bjc.2016.223
PMCID: PMC5023771

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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