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Article

Incidence of breast cancer and its subtypes in relation to individual and multiple low-penetrance genetic susceptibility loci.

JAMA - 28 Jul 2010

Reeves Gillian K, Travis Ruth C, Green Jane, Bull Diana, Tipper Sarah, Baker Krys, Beral Valerie, Peto Richard, Bell John, Zelenika Diana, Lathrop Mark

Abstract excerpt

CONTEXT: There is limited evidence on how the risk of breast cancer and its subtypes depend on low-penetrance susceptibility loci, individually or in combination. OBJECTIVE: To analyze breast cancer risk, overall and by tumor subtype, in relation to 14 individual single-nucleotide polymorphisms (SNPs) previously linked to the disease, and in relation to a polygenic risk score. DESIGN, SETTING, AND PARTICIPANTS:...

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PMID: 20664043
DOI: 10.1001/jama.2010.1042

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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