Article
Menopause accelerates biological aging.
Proceedings of the National Academy of Sciences of the United States of America - 16 Aug 2016
Levine Morgan E, Lu Ake T, Chen Brian H, Hernandez Dena G, Singleton Andrew B, Ferrucci Luigi, Bandinelli Stefania, Salfati Elias, Manson JoAnn E, Quach Austin, Kusters Cynthia D J, Kuh Diana, Wong Andrew, Teschendorff Andrew E, Widschwendter Martin, Ritz Beate R, Absher Devin, Assimes Themistocles L, Horvath Steve
Abstract excerpt
Although epigenetic processes have been linked to aging and disease in other systems, it is not yet known whether they relate to reproductive aging. Recently, we developed a highly accurate epigenetic biomarker of age (known as the "epigenetic clock"), which is based on DNA methylation levels. Here we carry out an epigenetic clock analysis of blood, saliva, and buccal epithelium using data from four large...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.