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Article

Peripheral blood toll-like receptor 4 correlates with rapid virological response to pegylated-interferon and ribavirin therapy in hepatitis C genotype 1 patients.

BMC gastroenterology - 25 Jul 2016

Lee Chuan-Mo, Hu Tsung-Hui, Lu Sheng-Nan, Wang Jing-Houng, Hung Chao-Hung, Chen Chien-Hung, Yen Yi-Hao

Abstract excerpt

BACKGROUND: Toll-like receptors (TLRs) are effectors of the innate immune system that are able to recognize hepatitis C virus (HCV) and give rise to an immune response. Failure of interferon (IFN)-α-based treatment is related to host immunity. Therefore, we sought to study the clinical importance of TLRs in HCV genotype 1 patients who received pegylated IFN (PEG-IFN) plus ribavirin (RBV) therapy. METHODS: We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27457659
DOI: 10.1186/s12876-016-0492-6
PMCID: PMC4960680

Genes

GAPDH
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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