Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Increased baseline proinflammatory cytokine production in chronic hepatitis C patients with rapid virological response to peginterferon plus ribavirin.

PloS one - 1 Jan 2013

Par Gabriella, Szereday Laszlo, Berki Timea, Palinkas Laszlo, Halasz Melinda, Miseta Attila, Hegedus Geza, Szekeres-Bartho Julia, Vincze Aron, Hunyady Bela, Par Alajos

Abstract excerpt

BACKGROUND: Chronic hepatitis C (CHC) patients achieving rapid virological response (RVR) on PEG-IFN/ribavirin (P/R) therapy have high chance of sustained virological response (SVR). To analyze host immunological factors associated with RVR, viral kinetics, phenotype distribution and Th1/Th2 cytokine production by peripheral blood mononuclear cells (PBMC) were studied prior to and during P/R therapy. METHODS:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Inflammation Mediators
Share to Interferon-alpha

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Killer Cells, Natural

Share to Leukocytes, Mononuclear

Share to Lymphocyte Activation

Share to Ribavirin

Share to T-Lymphocyte Subsets

Share to Toll-Like Receptor 4

Source

Open in PubMed Open full text

Identifiers

PMID: 23874444
DOI: 10.1371/journal.pone.0067770
PMCID: PMC3706447

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Increased baseline proinflammatory cytokine production in chronic hepatitis C patients with rapid virological response to peginterferon plus ribavirin.PMID 23874444Read ↗

Sustained virological response to peginterferon plus ribavirin in chronic hepatitis C genotype 1 patients is associated with a persistent Th1 immune response.Semantic proximity Read ↗

Peripheral blood toll-like receptor 4 correlates with rapid virological response to pegylated-interferon and ribavirin therapy in hepatitis C genotype 1 patients.Semantic proximity Read ↗

Maintenance of T1 response as induced during PEG-IFNalpha plus ribavirin therapy controls viral replication in genotype-1 patients with chronic hepatitis C.Semantic proximity Read ↗

Role of Th1/Th2 cytokines in serum on the pathogenesis of chronic hepatitis C and the outcome of interferon therapy.Semantic proximity Read ↗

Immunological dynamics associated with rapid virological response during the early phase of type I interferon therapy in patients with chronic hepatitis C.Semantic proximity Read ↗

Ribavirin upregulates interleukin-12 receptor and induces T cell differentiation towards type 1 in chronic hepatitis C.Semantic proximity Read ↗

Elevated on-treatment levels of serum IFN-gamma is associated with treatment failure of peginterferon plus ribavirin therapy for chronic hepatitis C.Semantic proximity Read ↗

Cytokines as predictors for sustained response and as markers for immunomodulation in patients with chronic hepatitis C.Semantic proximity Read ↗

Toll-IL1 receptor-mediated innate immune responses vary across HBV genotype and predict treatment response to pegylated-IFN in HBeAg-positive CHB patients.Semantic proximity Read ↗

Deciphering the Significance of Plasma Chemokines as Prognostic Biomarkers in Pegylated IFN-Α-2a /Ribavirin-Treated Chronic Hepatitis C Genotype 4 Patients.Semantic proximity Read ↗

Hepatic Toll-Like Receptor 3 expression in chronic hepatitis C genotype 1 correlates with treatment response to peginterferon plus ribavirin.Semantic proximity Read ↗

Role of TLRs and IL-6 in the outcome of chronic hepatitis C treatment in Tunisian population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.