Article
RNA structure in splicing: An evolutionary perspective.
RNA biology - 1 Sept 2016
Lin Chien-Ling, Taggart Allison J, Fairbrother William G
Abstract excerpt
Pre-mRNA splicing is a key post-transcriptional regulation process in which introns are excised and exons are ligated together. A novel class of structured intron was recently discovered in fish. Simple expansions of complementary AC and GT dimers at opposite boundaries of an intron were found to form a bridging structure, thereby enforcing correct splice site pairing across the intron. In some fish introns, the...
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