Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The prospect of precision therapy for renal cell carcinoma.

Cancer treatment reviews - 1 Sept 2016

Ciccarese Chiara, Brunelli Matteo, Montironi Rodolfo, Fiorentino Michelangelo, Iacovelli Roberto, Heng Daniel, Tortora Giampaolo, Massari Francesco

Abstract excerpt

The therapeutic landscape of renal cell carcinoma (RCC) has greatly expanded in the last decade. From being a malignancy orphan of effective therapies, kidney cancer has become today a tumor with several treatment options. Renal cell carcinoma (RCC) is a metabolic disease, being characterized by the dysregulation of metabolic pathways involved in oxygen sensing (VHL/HIF pathway alterations and the subsequent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to AMP-Activated Protein Kinases
Share to Fumarate Hydratase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glucose Transporter Type 1

Share to Glucose Transporter Type 4

Share to Hepatocyte Growth Factor

Share to Platelet-Derived Growth Factor

Share to Programmed Cell Death 1 Receptor

Share to Receptors, Fibroblast Growth Factor

Source

Identifiers

PMID: 27453294
DOI: 10.1016/j.ctrv.2016.07.003

Genes

EGF
HGF
MET
TSC1
VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The prospect of precision therapy for renal cell carcinoma.PMID 27453294Read ↗

The molecular code of kidney cancer: A path of discovery for gene mutation and precision therapy.Semantic proximity Read ↗

New strategies in renal cell carcinoma: targeting the genetic and metabolic basis of disease.Semantic proximity Read ↗

The Complex Interplay between Metabolic Reprogramming and Epigenetic Alterations in Renal Cell CarcinomaSemantic proximity Read ↗

Kidney cancer pathology in the new context of targeted therapy.Semantic proximity Read ↗

Identification of a novel papillary renal cell carcinoma molecular subtype characterized by HIF-pathway over-activationSemantic proximity Read ↗

Multiomics in Renal Cell Carcinoma: Current Landscape and Future Directions for Precision MedicineSemantic proximity Read ↗

The genetic basis of kidney cancer: a metabolic disease.Semantic proximity Read ↗

Renal cell carcinoma: new insights and challenges for a clinician scientist.Semantic proximity Read ↗

Renal Cell Cancer and ObesitySemantic proximity Read ↗

Lipid in Renal Carcinoma: Queen Bee to Target?Semantic proximity Read ↗

The metabolic basis of kidney cancer.Semantic proximity Read ↗

Targeting strategies in the treatment of fumarate hydratase deficient renal cell carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.