Article

Identification of a novel papillary renal cell carcinoma molecular subtype characterized by HIF-pathway over-activation

2025-01-27

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Purpose</h4> Papillary renal cell carcinoma (pRCC), the second most common subtype of renal cancer, exhibits heterogeneity in molecular features and response to targeted therapies, including antiangiogenic drugs. Discovering molecular biomarkers able to stratify pRCC patients into clinically relevant subgroups and understanding the underlying mechanisms are urgently needed to advance precis...

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Literature Corpus work: 5398c3b4-61ce-54b2-a2ce-a124b6ebe16f
DOI: 10.1101/2025.01.24.632989

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