Article
Vitamin D depletion does not affect key aspects of the preeclamptic phenotype in a transgenic rodent model for preeclampsia.
Journal of the American Society of Hypertension : JASH - 1 Jul 2016
Andersen Louise Bjørkholt, Golic Michaela, Przybyl Lukasz, Sorensen Grith Lykke, Jørgensen Jan Stener, Fruekilde Palle, von Versen-Höynck Frauke, Herse Florian, Højskov Carsten Schriver, Dechend Ralf, Christesen Henrik Thybo, Haase Nadine
Abstract excerpt
Maternal vitamin D deficiency is proposed as a risk factor for preeclampsia in humans. We tested the hypothesis that vitamin D depletion aggravates and high supplementation ameliorates the preeclampsia phenotype in an established transgenic rat model of human renin-angiotensin system-mediated preeclampsia. Adult rat dams, transgenic for human angiotensinogen (hAGT) and mated with male rats transgenic for human...
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