Article
Cadmium-induced preeclampsia-like phenotype in the rat is related to decreased progesterone synthesis in the placenta.
Xenobiotica; the fate of foreign compounds in biological systems - 1 Jun 2022
Zhang Xiaojie, Chen Kai, Meng Zhu, Jia Ru, Lian Feifei, Lin Feng
Abstract excerpt
Cadmium (Cd) is a toxic element, which is associated with preeclampsia (PE).We treated pregnant rats with cadmium chloride from gestational days (GDs) 9-12 to introduce the PE-like animal model. Maternal systolic blood pressures (SBPs) and body weights were measured on GDs 0, 5, 10, 15, and 20. Foetuses were delivered by Caesarean section on GD20. Then, the dams were sacrificed and the specimens were obtained....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.