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Article

Genetic variation in OPRD1 and the response to treatment for opioid dependence with buprenorphine in European-American females.

The pharmacogenomics journal - 1 Jun 2014

Clarke T-K, Crist R C, Ang A, Ambrose-Lanci L M, Lohoff F W, Saxon A J, Ling W, Hillhouse M P, Bruce R D, Woody G, Berrettini W H

Abstract excerpt

Two commonly prescribed treatments for opioid addiction are methadone and buprenorphine. Although these drugs show some efficacy in treating opioid dependence, treatment response varies among individuals. It is likely that genetic factors have a role in determining treatment outcome. This study analyses the pharmacogenetic association of six polymorphisms in OPRD1, the gene encoding the delta-opioid receptor, on...

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Identifiers

PMID: 24126707
DOI: 10.1038/tpj.2013.30
PMCID: PMC3988270

Genes

OPRD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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