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Transcriptome sequencing wide functional analysis of human mesenchymal stem cells in response to TLR4 ligand

22 Jul 2016

Abstract excerpt

Due to their multipotentiality and immunomodulation, human mesenchymal stem cells (hMSCs) are widely studied for the treatment of degenerative and inflammatory diseases. Transplantation of hMSCs to damaged tissue is a promising approach for tissue regeneration. However, the physiological mechanisms and regulatory processes of MSC trafficking to injured tissue are largely unexplored. Here, we evaluated the gene...

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PMID: 27444640
DOI: 10.1038/srep30311

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