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Integrative analysis of long non-coding RNA (lncRNA) and mRNA expression in TLR4-primed MSCs of ankylosing spondylitis

2020-10-20

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Ankylosing spondylitis (AS) is a chronic autoimmune disease, and the precise pathogenesis is largely unknown at present. Our previous study found that the expression of toll-like receptor 4 (TLR4) of mesenchymal stem cells from AS patients (AS-MSCs) was reduced and activation of TLR4 by lipopolysaccharide (LPS) could enhance the immunoregulatory ability of AS...

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Literature Corpus work
ba2124f3-b001-5dbf-8b38-f50b35b552d1
DOI
10.21203/rs.3.rs-45893/v2
Open publication

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Integrative analysis of long non-coding RNA (lncRNA) and mRNA expression in TLR4-primed MSCs of ankylosing spondylitisDOI 10.21203/rs.3.rs-45893/v2
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