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Identifying the key genes regulating mesenchymal stem cells chondrogenic differentiation: an in vitro study

15 Nov 2022

Abstract excerpt

BACKGROUND: Mesenchymal stem cells (MSCs) possess the potential to differentiate into chondrocytes, which makes them an ideal source for healing cartilage defects. Here, we seek to identify the essential genes participating in MSCs chondrogenesis. METHODS: Human MSCs were induced for chondrogenesis for 7, 14, and 21 days using a high-density micromass culture system, and RNA was extracted for RNA-seq. RESULTS: A...

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PMID: 36380336
DOI: 10.1186/s12891-022-05958-7

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