Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Test-Replicate Approach to Candidate Gene Research on Addiction and Externalizing Disorders: A Collaboration Across Five Longitudinal Studies.

Behavior genetics - 1 Sept 2016

Samek Diana R, Bailey Jennifer, Hill Karl G, Wilson Sylia, Lee Susanne, Keyes Margaret A, Epstein Marina, Smolen Andrew, Miller Michael, Winters Ken C, Hawkins J David, Catalano Richard F, Iacono William G, McGue Matt

Abstract excerpt

This study presents results from a collaboration across five longitudinal studies seeking to test and replicate models of gene-environment interplay in the development of substance use and externalizing disorders (SUDs, EXT). We describe an overview of our conceptual models, plan for gene-environment interplay analyses, and present main effects results evaluating six candidate genes potentially relevant to SUDs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Behavior, Addictive
Share to Child

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cooperative Behavior

Share to Genealogy and Heraldry

Share to Genetic Association Studies

Share to Longitudinal Studies

Share to Reproducibility of Results

Share to Substance-Related Disorders

Source

Open in PubMed Open full text

Identifiers

PMID: 27444553
DOI: 10.1007/s10519-016-9800-8
PMCID: PMC5060092

Genes

COMT
DRD2
DRD4
MAOA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Test-Replicate Approach to Candidate Gene Research on Addiction and Externalizing Disorders: A Collaboration Across Five Longitudinal Studies.PMID 27444553Read ↗

Clinical, Environmental, and Genetic Risk Factors for Substance Use Disorders: Characterizing Combined Effects across Multiple CohortsSemantic proximity Read ↗

Multi-ancestry genome-wide association study and meta-analysis of stimulant use disorder reveals biology and relationships to other psychiatric disordersSemantic proximity Read ↗

Psychometric and genetic architecture of substance use disorder and behavioral disinhibition measures for gene association studies.Semantic proximity Read ↗

Genetic and Environmental Interplay in Adolescent Substance Use DisordersSemantic proximity Read ↗

Genome-wide meta-analyses of cross substance use disorders in diverse populations.Semantic proximity Read ↗

Genome-wide association study in individuals of European and African ancestry and multi-trait analysis of opioid use disorder identifies 19 independent genome-wide significant risk loci.Semantic proximity Read ↗

Confluence of genes, environment, development, and behavior in a post Genome-Wide Association Study world.Semantic proximity Read ↗

Multi-ancestry meta-analysis of tobacco use disorder prioritizes novel candidate risk genes and reveals associations with numerous health outcomesSemantic proximity Read ↗

A common genetic network underlies substance use disorders and disruptive or externalizing disorders.Semantic proximity Read ↗

A Family-Based Genome Wide Association Study of Externalizing Behaviors.Semantic proximity Read ↗

Stability and change of genetic and environmental effects on the common liability to alcohol, tobacco, and cannabis DSM-IV dependence symptoms.Semantic proximity Read ↗

Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disordersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.