Article
Genomic analysis identified a potential novel molecular mechanism for high-altitude adaptation in sheep at the Himalayas.
Scientific reports - 22 Jul 2016
Gorkhali Neena Amatya, Dong Kunzhe, Yang Min, Song Shen, Kader Adiljian, Shrestha Bhola Shankar, He Xiaohong, Zhao Qianjun, Pu Yabin, Li Xiangchen, Kijas James, Guan Weijun, Han Jianlin, Jiang Lin, Ma Yuehui
Abstract excerpt
Sheep has successfully adapted to the extreme high-altitude Himalayan region. To identify genes underlying such adaptation, we genotyped genome-wide single nucleotide polymorphisms (SNPs) of four major sheep breeds living at different altitudes in Nepal and downloaded SNP array data from additional Asian and Middle East breeds. Using a di value-based genomic comparison between four high-altitude and eight lowland...
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