Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

FGF5 and EPAS1 gene polymorphisms are associated with high-altitude adaptation in Nepalese goat breeds.

Animal science journal = Nihon chikusan Gakkaiho - 1 Jan 2021

Sasazaki Shinji, Tomita Koichiro, Nomura Yuto, Kawaguchi Fuki, Kunieda Tetsuo, Shah Manoj Kumar, Mannen Hideyuki

Abstract excerpt

Several studies have reported the gene polymorphisms associated with high-altitude adaptation in goats. The FGF5 gene is a regulator in the hair-growth and a SNP c.-253G>A located within 5'UTR has been reported to cause long-haired phenotype. The EPAS1 gene is a transcription factor for various genes that have hypoxia-adaptive functions and a nonsynonymous SNP (Q579L) located in exon 5 has been reported to be...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Altitude
Share to Asian People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to EPAS1 gene

Share to Gene Frequency

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 34585489
DOI: 10.1111/asj.13640

Genes

EPAS1
FGF5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

FGF5 and EPAS1 gene polymorphisms are associated with high-altitude adaptation in Nepalese goat breeds.PMID 34585489Read ↗

Genome-wide analysis reveals adaptation to high altitudes in Tibetan sheep.Semantic proximity Read ↗

EPAS1 Gain-of-Function Mutation Contributes to High-Altitude Adaptation in Tibetan HorsesSemantic proximity Read ↗

The three missense mutations of EPAS1, IL37 and EEF1D genes associated with high-altitude adaptation in Chinese cattle.Semantic proximity Read ↗

Genetic variants in EPAS1 contribute to adaptation to high-altitude hypoxia in Sherpas.Semantic proximity Read ↗

Hypobaric hypoxia drives selection of altitude-associated adaptative alleles in the Himalayan population.Semantic proximity Read ↗

Population History and Altitude-Related Adaptation in the SherpaSemantic proximity Read ↗

A non-synonymous SNP with the allele frequency correlated with the altitude may contribute to the hypoxia adaptation of Tibetan chicken.Semantic proximity Read ↗

High-impact Genetic Variants in EGLN1, EPAS1, and Other Genes Identified in Mountaineers by Exome Sequencing.Semantic proximity Read ↗

Downregulation of EPAS1 and EGLN1 mRNA Expression Associated With High-Altitude Adaptive Genetic Variants in Sherpa Highlanders.Semantic proximity Read ↗

Adaptation to High Altitude: Phenotypes and GenotypesSemantic proximity Read ↗

Andean and Tibetan patterns of adaptation to high altitude.Semantic proximity Read ↗

Exome sequencing reveals genetic differentiation due to high-altitude adaptation in the Tibetan cashmere goat (Capra hircus).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.