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Article

How genome-wide SNP-SNP interactions relate to nasopharyngeal carcinoma susceptibility.

PloS one - 1 Jan 2013

Su Wen-Hui, Yao Shugart Yin, Chang Kai-Ping, Tsang Ngan-Ming, Tse Ka-Po, Chang Yu-Sun

Abstract excerpt

This study is the first to use genome-wide association study (GWAS) data to evaluate the multidimensional genetic architecture underlying nasopharyngeal cancer. Since analysis of data from GWAS confirms a close and consistent association between elevated risk for nasopharyngeal carcinoma (NPC) and major histocompatibility complex class 1 genes, our goal here was to explore lesser effects of gene-gene...

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Identifiers

PMID: 24376627
DOI: 10.1371/journal.pone.0083034
PMCID: PMC3871583

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